Associate Professor & Consultant Neurosurgeon
Office : +603 7967 ____
Email : nvairavan@um.edu.my
UMExpert Link: https://umexpert.um.edu.my/nvairavan
Publons Link: https://publons.com/researcher/1605758/vairavan-narayanan/
Research Keywords : Advanced Neuroimaging | Neurogenomics | Neurosurgery
Research Summary
Brain Injury is an external or internal disruption of brain homeostasis resulting in physical, functional or cognitive changes to the central nervous system. I am specifically interested in 3 different causes of brain injury – namely, Epilepsy, Brain tumors and Traumatic Brain injury.
The pathophysiology of Brain Injury works via similar pathways of genetic, biochemical and structural damage. My aim is to study these causative mechanisms to establish improved diagnostics, prognostics as well as therapeutic interventions in minimizing the long term outcome of Brain Injury
Main Research Interest / Goals
- Development of advanced radiological identifiers for intractable epilepsy and aid surgical planning
- Identify Radiogenomic signatures of high grade gliomas for diagnosis, surgical planning and prognostication
- Develop extra-CNS biomarkers for early identification of metastases
- Develop radiogenomic prognosticators for structural damage in TBI
Selected Publications
- Seow P, Narayanan V, Romelean RJ et al. (2019) Lipid Fraction Derived From MRI In- and Opposed-Phase Sequence as a Novel Biomarker for Predicting Survival Outcome of Glioma. Acad Radiol. 2019 May 31. doi: 10.1016/j.acra.2019
- Narayanan V,Jayapalan RR, Singh Sidhu A et al. (2019) Single Port Endoscope-Assisted Excision of Forehead Lesions: An Innovative Way of Improving the Optical Cavity. J Craniofac Surg. 2019 May/Jun;30(3):841-842.
- Seow P, Narayanan V,Hernowo AT et al. (2018) Quantification and visualization of lipid landscape in glioma using in -and opposed-phase imaging. Neuroimage Clin. 2018 Aug 7;20:531-536.
- Veeramuthu V, Narayanan V, Ramli N et al. (2017) Neuropsychological Outcomes in Patients with Complicated Versus Uncomplicated Mild Traumatic Brain Injury: 6-Month Follow-Up. World Neurosurg. 2017 Jan;97:416-423.
- Narayanan V, Veeramuthu V, Ahmad-Annuar A et al. (2016) Missense Mutation of Brain Derived Neurotrophic Factor (BDNF) Alters Neurocognitive Performance in Patients with Mild Traumatic Brain Injury: A Longitudinal Study.PLoS One. 2016 Jul 20;11(7)
- Waran V, Narayanan V, Karuppiah R et al. (2014) Utility of multimaterial 3D printers in creating models with pathological entities to enhance the training experience of neurosurgeons. J Neurosurg. 2014 Feb;120(2):489-92.